ACTEMRA 162 mg/0.9 ml solution for injection in pre-filled syringe

Product Description

ACTEMRA 162 mg/0.9 ml solution for injection in pre-filled syringe is a vital prescription medication designed to treat various inflammatory and autoimmune conditions. This specialized formulation delivers Tocilizumab, a monoclonal antibody that targets the interleukin-6 (IL-6) receptor, reducing inflammation and managing disease progression. As seen on platforms like Nahdi Online, Actemra is recognized for its role in therapeutic management, offering a convenient pre-filled syringe for subcutaneous administration, often empowering patients to manage their treatment at home after proper training. This product is carefully manufactured by Roche, a leader in pharmaceutical innovation, ensuring high standards of quality and efficacy.

Benefits of Use

• Reduces the signs and symptoms of inflammatory diseases such as rheumatoid arthritis (RA), giant cell arteritis (GCA), polyarticular juvenile idiopathic arthritis (PJIA), and systemic juvenile idiopathic arthritis (SJIA).
• Helps prevent joint damage and improves physical function in patients with rheumatoid arthritis.
• Effectively manages severe inflammation, including cytokine release syndrome (CRS) in specific contexts.
• Offers the convenience of a pre-filled syringe for ease of self-administration, following healthcare provider guidance.

How to Use

Administer ACTEMRA 162 mg/0.9 ml subcutaneously as directed by your healthcare professional. Follow these general steps for proper injection:

1. Prepare the Syringe: Remove the pre-filled syringe from the refrigerator at least 30 minutes before injection to allow it to reach room temperature. Do not use external heat sources to warm it.
2. Inspect the Solution: Before use, visually inspect the solution in the syringe. It should be clear to slightly yellowish. Do not use if it is cloudy, discolored, or contains large particles.
3. Choose and Clean Injection Site: Select a suitable injection site, typically on the thigh or abdomen. Rotate injection sites with each dose. Clean the chosen area thoroughly with an alcohol swab and let it air dry completely.
4. Administer the Injection: Gently pinch a fold of skin at the cleaned site. Hold the syringe firmly and insert the needle completely into the skin at a 45-degree angle. Slowly push the plunger all the way down until all the medication is injected.
5. Withdraw and Dispose: Release the pinched skin and carefully withdraw the needle. Immediately dispose of the used syringe in a designated sharps container. Do not recap the needle.
6. Post-Injection Care: Do not rub the injection site. Apply gentle pressure with a cotton ball if needed.

Caution & Warnings

• Prescription Medication: ACTEMRA is a prescription-only medication. Use strictly as prescribed by your doctor.
• Risk of Serious Infections: Treatment with Actemra may increase your risk of serious infections (e.g., tuberculosis, fungal, bacterial, or viral infections), which can be severe and may lead to hospitalization or death. Report any signs of infection (fever, cough, shortness of breath, skin sores, unusual fatigue) to your doctor immediately.
• Gastrointestinal Perforations: Increased risk of gastrointestinal perforations has been observed, especially in patients with a history of diverticulitis. Seek immediate medical attention for any new abdominal pain.
• Liver Enzyme Elevations: Liver enzyme elevations can occur. Regular monitoring of liver function tests is recommended during treatment.
• Vaccinations: Ensure you are up-to-date with all immunizations before starting Actemra. Live vaccines should not be administered during treatment.
• Hypersensitivity Reactions: Severe hypersensitivity reactions, including anaphylaxis, have been reported.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the potential risks. Discuss with your doctor.
• Storage: Keep out of reach of children. Store as directed to maintain product efficacy.

Ingredients

• Active Ingredient: Tocilizumab 162 mg
• Other Ingredients: L-histidine, L-histidine hydrochloride monohydrate, L-arginine hydrochloride, L-methionine, polysorbate 80, water for injection.

Product Details

• Strength: 162 mg/0.9 ml
• Dosage Form: Solution for injection in pre-filled syringe
• Manufacturer: Roche
• Storage: Store in a refrigerator (2°C to 8°C). Protect from light. Do not freeze.
• Package Size: Typically supplied as a carton containing 4 pre-filled syringes.